Determination of Cross-Directional and Cross-Wall Variations of Passive Biaxial Mechanical Properties of Rat Myocardia

Heart myocardia are critical to the facilitation of heart pumping and blood circulating around body. The biaxial mechanical testing left ventricle (LV) has been extensively utilised build computational model whole with little importance given unique properties right (RV) cardiac septum (SPW). Most those studies focussed on LV then applied obtained characteristics a few modifications side heart. However, assumption that applies RV contested over time realisation possesses its own widely distinct from This paper evaluates passive property differences in three main walls rat based tensile test data. Fifteen mature Wistar rats weighing 225 ± 25 g were euthanised by inhalation 5% halothane. hearts excised after which all top chambers comprising two atria, pulmonary vena cava trunks, aorta, valves dissected out. Then, 5 × mm sections middle each wall carefully surgical knife avoid overly pre-straining specimens. specimens subjected testing. elastic moduli, peak stresses toe region at 40% strain, anisotropy indices, as well stored strain energy linear up used for statistical significance tests. findings this study are: (1) SPW tissues have relatively shorter regions 10–15% compared tissue, whose extends twice much that; (2) higher storage despite being lower stiffness than RV; (3) highest along both directions, might be directly related high level anisotropy. These findings, though specific animal species similar age same body mass, emphasise application wall-specific material parameters obtain accurate ventricular hyperelastic models. further enhance our understanding desired behaviour different walls.